Novel proton acceptor immonium-type coupling reagents: application in solution and solid-phase peptide synthesis.
نویسندگان
چکیده
A novel proton acceptor coupling reagent shows superiority to those described previously. The oxygen in the carbocation moiety confers more solubility to the reagent. Furthermore, it enhances coupling yields and decreases racemization, allowing the use of 1 equiv of base.
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ورودعنوان ژورنال:
- Organic letters
دوره 9 22 شماره
صفحات -
تاریخ انتشار 2007